La Comadre 1260 AM is a radio station based in Mexico City, Mexico, owned by Grupo ACIR. It broadcasts regional Mexican music, including grupera, norteña, and banda genres. The station's slogan is "¡Puros Éxitos, Puros Comadrazos!" (Pure Hits, Pure Comadrazos!).

Originally launched in 1930 as Radio Capital, it underwent several format changes over the years. In 2015, it adopted its current name and regional Mexican music format. La Comadre 1260 AM features popular music programming along with entertainment segments hosted by its team of announcers.

One of the station's notable programs is "La Hora de Los Tigres Del Norte" (The Hour of Los Tigres Del Norte), which airs weekdays from 12:00 to 13:00. The station aims to provide listeners with current information, relevant news, and entertainment, alongside its musical offerings.