Radio Bío-Bío is a prominent Chilean radio station founded in 1966 in Concepción, Chile. It has grown to become one of the most listened-to radio networks in the country, with broad national coverage. The station covers news, sports, music, economics, and international relations.

Originally established as a local station in Concepción, Radio Bío-Bío began expanding across Chile in the 1990s. It now operates on over 40 frequencies nationwide, with autonomous stations in major cities including Santiago, Valparaíso, Temuco, and Puerto Montt.

Known for its independent journalism, Radio Bío-Bío is not affiliated with any political, religious, or economic groups. Its programming includes news broadcasts, sports coverage, talk shows, and music. Popular programs include "Radiograma", "Podría ser peor", and "Expreso Bío Bío".

The station's online presence, BioBioChile, has become one of Chile's most visited news websites since its launch in 2009. Radio Bío-Bío prides itself on its slogan "Bío-Bío, La Radio" and its commitment to providing timely, accurate information to its listeners across Chile.